Germoloids vs Anusol: comparing options

Published 13 March 2026 ·Last reviewed 13 March 2026 by the editorial team ·How we create our content

At a glance

Germoloids and Anusol are two of the most commonly used over-the-counter products for hemorrhoid symptoms in the UK. They take different approaches to symptom relief, and understanding what each contains helps you choose the better option for your specific symptoms.

This guide compares the two products practically — what they contain, what they are best for, and what people report about using them.

What each contains

Germoloids

The key active ingredient in Germoloids is lidocaine — a local anaesthetic. This is combined with zinc oxide, which has mild astringent and protective properties.

Germoloids is available as:

  • Cream
  • Ointment
  • Suppositories

Anusol

Anusol contains zinc oxide, bismuth subgallate, and balsam of Peru. These are astringent and protective ingredients designed to soothe, protect, and help reduce irritation.

Anusol is available as:

  • Cream
  • Ointment
  • Suppositories

There is also Anusol Plus HC, which adds hydrocortisone (a mild steroid) for additional anti-inflammatory effect. This version may require a pharmacist consultation.

How they compare

FeatureGermoloidsAnusol
Pain reliefStrong (lidocaine)Mild (astringent action)
Itch reliefGood (lidocaine numbing)Moderate (soothing/protective)
Barrier protectionYes (zinc oxide)Yes (zinc oxide, bismuth)
Anti-inflammatoryMinimalMinimal (Plus HC version has this)
Best forPain-dominant symptomsGeneral discomfort and irritation
FormsCream, ointment, suppositoriesCream, ointment, suppositories

Choosing between them

Choose Germoloids if

  • Pain is your primary symptom — the lidocaine provides effective temporary numbing
  • Itching is severe — the anaesthetic dulls the itch sensation
  • You need quick relief — the numbing effect is relatively fast-acting
  • Post-bowel-movement pain is your main concern

Choose Anusol if

  • Your symptoms are mild — general discomfort rather than significant pain
  • Irritation and soreness are the main issues — the barrier protection is helpful
  • You want to avoid anaesthetic ingredients — Anusol (standard) contains no lidocaine
  • You need a product for longer-term, mild use — the gentler formulation suits ongoing mild symptoms
  • Swelling is a concern — Anusol Plus HC (with hydrocortisone) can address mild inflammation, though it should not be used long-term

What people describe

Germoloids users

  • “The numbing is noticeable and provides real relief”
  • “Best for the acute pain after a bowel movement”
  • “Feels more effective than Anusol for bad days”
  • “Can sometimes cause a slight tingling or warming sensation”

Anusol users

  • “Gentle and soothing — good for everyday use”
  • “Provides a protective barrier that reduces irritation”
  • “Less intense than Germoloids — suits milder symptoms”
  • “The suppositories are useful for internal symptoms”
  • “Plus HC version helped when there was swelling”

Practical guidance

Using either product

  • Clean the area gently with warm water before application
  • Apply a thin layer — more is not better
  • Wash hands before and after
  • Follow the product instructions for frequency of use
  • Use consistently for a few days before judging effectiveness

Duration of use

  • Both products are designed for short-term symptom relief
  • If symptoms persist beyond two weeks of consistent use, reassess with a pharmacist or doctor
  • Anusol Plus HC (with hydrocortisone) should not be used for more than seven days without clinical guidance
  • Ongoing reliance on any topical product suggests the underlying condition needs attention

When neither is enough

If over-the-counter products are not providing adequate relief, the next steps typically include:

  • A conversation with a pharmacist about stronger options
  • A visit to your GP for assessment and potentially prescription treatment
  • Addressing the underlying factors — diet, hydration, toilet habits, and activity levels
  • A referral to a specialist if the condition is more complex

The broader picture

Both Germoloids and Anusol manage symptoms. They provide relief while you work on the factors that are causing or maintaining the hemorrhoids. The most effective approach combines topical relief with dietary changes, adequate hydration, proper toilet habits, and regular movement. A topical product on its own is rarely a complete solution.

Common questions

Is Germoloids or Anusol better for hemorrhoids?

It depends on your primary symptom. Germoloids contains a local anaesthetic (lidocaine) which makes it better for pain and itching. Anusol focuses on soothing and protecting the area with astringent and barrier ingredients. For significant pain, people tend to prefer Germoloids. For general protection and mild discomfort, Anusol is often sufficient.

Can I use both?

Using both products simultaneously is generally not recommended without pharmacist or clinical guidance, as combining products can lead to overuse of certain ingredients. If one product is not providing adequate relief, it is better to switch to the other or discuss alternatives with a pharmacist rather than layering them.

Do they treat hemorrhoids or just manage symptoms?

Both products manage symptoms — they do not cure or shrink hemorrhoids. They provide temporary relief while the body heals (or while you implement other management strategies). Long-term hemorrhoid management involves addressing the underlying factors through diet, hydration, toilet habits, and potentially clinical treatment.

Are there suppository versions?

Both Germoloids and Anusol are available in suppository form as well as cream or ointment. Suppositories are designed for internal hemorrhoids and deliver the active ingredients directly inside the anal canal. Your pharmacist can advise which form is most appropriate for your symptoms.

When to seek care Heavy bleeding or feeling faint? Get emergency help now. Emergency: 911

Not sure how urgent it is? Get help today.

  1. Emergency

    Heavy bleeding, black tarry stools, feeling faint, severe pain or trouble breathing.

    Call 911 or go to the ER.

  2. Today

    Fever, pain getting worse, a hot swollen lump, or trouble passing urine.

    Call your doctor or go to urgent care.

  3. Soon

    Bleeding or bowel changes nobody has checked, or anything lasting 3 weeks.

    Book a doctor’s appointment.

Feeling overwhelmed? Call or text 988, any time.

See all the signs

For this topic, get medical advice if you notice:

  • Rectal bleeding — always worth getting checked
  • Unexplained weight loss
  • Persistent change in bowel habits
  • Severe or worsening pain

Recording how you feel is not the same as being checked. These are the signs that need a doctor’s attention.

Call 911 or go to the emergency room now if you have:

  • bleeding that will not stop, a lot of blood (the toilet water turns red, or you pass large clots), or any bleeding with feeling faint or dizzy
  • fainting, a racing heart or trouble breathing
  • confusion or slurred speech, extreme shivering, no urine in a day, or blotchy skin
  • sudden severe belly pain, or a swollen, hard belly with vomiting or not passing stool or gas
  • you cannot pass urine at all, or your bladder feels full and painful and you can’t empty it
  • redness, swelling or severe pain spreading quickly around your anus, genitals or groin, especially with a fever or feeling very ill
  • a fever with a painful swelling near your anus if you have diabetes or a weakened immune system (for example, from chemotherapy or transplant medicines)
  • black, tarry stools

Call your doctor or go to urgent care today (or the ER if you can’t be seen today) if you have:

  • a temperature of 100.4°F (38°C) or higher, chills, vomiting, or feeling generally unwell
  • pain that is getting worse over days, or severe pain that stops you sitting or sleeping
  • a hot, swollen or very tender lump near your anus or at the top of the crease between your buttocks, or foul-smelling discharge
  • trouble urinating
  • bleeding that is getting heavier or more frequent, or blood mixed into your stool
  • feeling much more tired than usual, looking pale, or getting out of breath more easily than you used to
  • not passing stool for several days, or new belly pain

Make an appointment with your doctor if:

  • you have never had these symptoms checked by a doctor or nurse — whatever your age
  • you have had rectal bleeding for more than 3 weeks
  • your bowel movements have been looser, thinner or more frequent than usual for 3 weeks or more, or you have lost weight without trying
  • symptoms have not settled after a week or so, or keep coming back
  • you notice a new lump near your anus, between your buttocks or in your belly, or an itch or discharge that does not clear
  • you have new leakage or trouble controlling your bowels
  • you are 45 or over, or have a family history of bowel cancer or inflammatory bowel disease, and any of these symptoms are new for you

If you are unsure, it is always reasonable to ask. If things feel overwhelming, call or text 988 (Suicide & Crisis Lifeline) or chat at 988lifeline.org, any time. If you don’t feel safe, call 911.

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Discreet symptom tracking

Symptoms that come and go? Keep track, day by day.

For hemorrhoids, fissures, fistulas and other anal and rectal problems. A short, discreet email asks how things have been, and saves each answer, so you can look back at every flare and every good week in your own words. If you haven’t had your symptoms checked, see your doctor first.

  • About ten seconds a check-in. No app, no password.
  • Nothing in the subject or preview says what it’s about.
  • Each Sunday, a link to your week, ready for your next appointment.

Your notes

Your check-in

Takes about ten seconds.

20:00
Example. Nothing on the lock screen hints at symptoms or conditions.

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