Anusol vs Germoloids: OTC compared

At a glance

Anusol and Germoloids are two of the most widely available over-the-counter hemorrhoid treatments in the UK. Both are available in various formulations (cream, ointment, suppositories), and both aim to relieve hemorrhoid symptoms. But they contain different active ingredients and work in slightly different ways.

This guide compares the two to help you make an informed choice.

What they contain

Anusol range

The Anusol range includes several products with different formulations:

Anusol cream/ointment/suppositories — contains zinc oxide, bismuth subgallate, balsam of Peru, and bismuth oxide. These ingredients provide:

• A protective barrier over the affected area
• Mild astringent action to reduce moisture
• Soothing and anti-inflammatory properties

Anusol Plus HC — adds hydrocortisone, a mild steroid that reduces inflammation and itching. Available over the counter in the UK for short-term use.

Germoloids range

Germoloids cream/ointment/suppositories — contains lidocaine (a local anaesthetic) and zinc oxide. These provide:

• Numbing of the affected area for pain relief
• A protective barrier
• Mild astringent action

Germoloids HC spray — adds hydrocortisone in a spray format.

The key differences

What people report

Anusol

People who prefer Anusol commonly describe:

• Good general soothing effect
• Helpful for mild itching and irritation
• The ointment formulation being better for overnight use
• The suppositories being useful for internal symptoms
• A gentle product that rarely causes irritation

Germoloids

People who prefer Germoloids commonly describe:

• Better pain relief because of the numbing effect
• Useful during acute flares when pain is the main symptom
• The spray being convenient for application without touching the area
• The numbing wearing off after a few hours, requiring reapplication

General patterns

• People with predominantly itching and irritation tend to prefer Anusol
• People with predominantly pain tend to prefer Germoloids
• The hydrocortisone versions of both are described as more effective for inflammation
• Neither is described as dramatically better than the other — personal preference and symptom profile guide the choice

Practical advice

Choosing between them

• If your main symptom is pain — Germoloids (with lidocaine) may provide more immediate relief
• If your main symptom is itching or general irritation — Anusol may be sufficient
• If your main symptom is inflammation — the HC (hydrocortisone) version of either may be most helpful
• If you have not tried either before, starting with one and giving it several days is more useful than switching rapidly

Using them effectively

• Apply after a bowel movement and after cleaning the area gently
• Follow the dosing instructions on the packaging
• Do not use HC products for more than seven days without medical guidance
• Use alongside conservative measures — fibre, hydration, sitz baths
• If symptoms persist after a week of consistent use, see your GP

When OTC products are not enough

Over-the-counter products are appropriate for mild to moderate hemorrhoid symptoms. See a clinician if:

• Symptoms are severe or worsening
• There is significant bleeding
• Products are not providing relief after a week
• You are unsure whether your symptoms are caused by hemorrhoids
• You need treatment during pregnancy (check with your midwife or GP first)

The bottom line

Both Anusol and Germoloids are reasonable over-the-counter options for hemorrhoid symptom relief. They work in slightly different ways — Anusol soothing and protecting, Germoloids numbing and protecting. Neither cures hemorrhoids; both provide temporary comfort while the underlying condition is managed through diet, hydration, and toilet habits. If neither is providing sufficient relief, the next step is a conversation with your GP.